Stiff-Man Syndrome and Variants

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منابع مشابه

Stiff-man syndrome and variants: clinical course, treatments, and outcomes.

BACKGROUND Little information is available about the incidence of stiff-man syndrome (SMS) (the classic form or its variants) or about long-term treatment responses and outcomes. OBJECTIVE To comprehensively describe the characteristics of a cohort of patients with SMS. DESIGN Observational study. SETTING Mayo Clinic, Rochester, Minnesota. PATIENTS Ninety-nine patients with classic SMS ...

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Jerking stiff-man syndrome.

A female patient had permanent axial muscular rigidity similar to the "stiff-man syndrome", together with axial myoclonus triggered by stretch reflexes and by supramaximal stimulation of the supraorbital nerve. The disorder responded to treatment with diazepam and baclofen. This disorder bore a marked similarity to the so-called "jerking stiff-man syndrome".

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Stiff man syndrome and related conditions.

The stiff man syndrome (SMS) and its variants, focal SMS, stiff limb (or leg) syndrome (SLS), jerking SMS, and progressive encephalomyelitis with rigidity and myoclonus (PERM), appear to occur more frequently than hitherto thought. A characteristic ensemble of symptoms and signs allows a tentative clinical diagnosis. Supportive ancillary findings include (1) the demonstration of continuous musc...

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The 'stiff man syndrome' in a boy.

In October, 1958, a Chinese boy, aged 7 years, was transferred to the Children's Unit with a diagnosis of recurrent tetanus. According to the mother, he had been ill intermittently since 1957 when he was first admitted to hospital complaining of stiffness of the body and inability to open his mouth. He apparently recovered from this illness, but was readmitted on two further occasions with simi...

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Stiff man syndrome with invasive thymic carcinoma.

Stiff man syndrome is a rare disease characterized by painful chronic spasms in the muscle and skeletal system. This syndrome is an autoimmune neurologic disorder which is associated with thymoma. We treated a 32-year-old male patient with a type C thymoma (based on the World Health Organization classification) who had stiff man syndrome. The patient underwent an extended thymectomy which broug...

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ژورنال

عنوان ژورنال: Archives of Neurology

سال: 2012

ISSN: 0003-9942

DOI: 10.1001/archneurol.2011.991